Caffeic Acid Phenethyl Ester Is a Potential Therapeutic Agent for Oral Cancer

Head and neck cancers, which affect 650,000 people and cause 350,000 deaths per year, is the sixth leading cancer by cancer incidence and eighth by cancer-related death worldwide. Oral cancer is the most common type of head and neck cancer. More than 90% of oral cancers are oral and oropharyngeal squamous cell carcinoma (OSCC). The overall five-year survival rate of OSCC patients is approximately 63%, which is due to the low response rate to current therapeutic drugs. In this review we discuss the possibility of using caffeic acid phenethyl ester (CAPE) as an alternative treatment for oral cancer. CAPE is a strong antioxidant extracted from honeybee hive propolis. Recent studies indicate that CAPE treatment can effectively suppress the proliferation, survival, and metastasis of oral cancer cells. CAPE treatment inhibits Akt signaling, cell cycle regulatory proteins, NF-κB function, as well as activity of matrix metalloproteinase (MMPs), epidermal growth factor receptor (EGFR), and Cyclooxygenase-2 (COX-2). Therefore, CAPE treatment induces cell cycle arrest and apoptosis in oral cancer cells. According to the evidence that aberrations in the EGFR/phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) signaling, NF-κB function, COX-2 activity, and MMPs activity are frequently found in oral cancers, and that the phosphorylation of Akt, EGFR, and COX-2 correlates to oral cancer patient survival and clinical progression, we believe that CAPE treatment will be useful for treatment of advanced oral cancer patients.     

硅微纳结构及其在新型太阳电池中的应用

综述了近年来各种硅微纳结构的特征和制备技术,介绍了其在新型太阳电池中的应用现状与前景.首先,阐述了硅微纳结构在传统p-n结、新型径向p-n结以及异质结太阳电池结构设计中的研究进展;其次,从光吸收增强、表面修饰及钝化的角度,分析了硅微纳结构太阳电池的增效措施;最后,提出了柔性硅微纳结构太阳电池开发的新思路.     

High-Temperature Deformation Behavior of MnS in 1215MS Steel

The effect of manganese sulfide (MnS) inclusions on the machinability of free-cutting steel is based on their morphology, size and distribution. Furthermore, the plasticity of MnS is high during the hot working caused different characterization of MnS. In this study, the deformation behavior of MnS in 1215MS steel after a thermomechanical process was investigated at 1323 K. The microstructures of MnS inclusions were characterized by optical microscopy, scanning electron microscopy, energy-dispersive spectrometry, and electron backscattering diffraction (EBSD). As the thickness reduction of the inclusions increased from 10 to 70%, their average aspect ratio increased from 1.20 to 2.39. In addition, the deformability of MnS inclusions was lower than that of the matrix. The possible slip systems of A, B, C, and D plane traces were \(\left( {\bar{1}0\bar{1}} \right)\left[ {\bar{1}01} \right],\left( {10\bar{1}} \right)\left[ {101} \right],\left( {011} \right)\left[ {01\bar{1}} \right]\), and \(\left( {110} \right)\left[ {1\bar{1}0} \right]\). Furthermore, the EBSD measurements suggested that slip planes in MnS inclusions occur on {110} planes.     

热卷箱在1780热轧带钢生产线的应用

在热轧带钢生产线中,热卷箱对提高带钢质量和成材率、降低能耗至关重要。介绍了承钢1780热轧带钢生产线中热卷箱的设备组成、工作方式和使用效果,针对生产中出现的工艺参数选择、液压设备和检测设备存在的故障问题,逐一找出原因,提出了相应的解决措施。     

Processing and failure behavior of carbon‐nanotube composites in sheet forms

In their original forms, carbon nanotubes (CNT) are spatially entangled. To make CNT papers (CNTPs), the CNT agglomerates must be dispersed and re‐entangled into a planar sheet. The processing characteristics are very different from those of traditional buck‐form nanocomposites. This article examines the processing, micro‐structures, and failure behavior of the CNTP composites. The CNTPs were first made by a dispersion and filtering process. Then, an epoxy resin was added into the CNTP by using a vacuum bag method. Different CNT weights were employed to make the CNTPs with different thicknesses and areal weights. The CNTP allows direct resin impregnation along the thickness direction and avoids the difficulty of dispersing CNTs in the viscous resin. The CNT content can be much higher than that attainable in traditional bulk CNT composites. Both tensile and tearing tests were conducted, and the fracture behaviors were examined. POLYM. COMPOS., 37:1564–1571, 2016. © 2014 Society of Plastics Engineers     

Assessment of LTE Wireless Accessing for Managing Traffic Flow of IoT Services

Mobile Networks and Applications - There is a tremendous growth in the traffic of the Internet of Things (IoT) devices. Some of the IoT application scenarios may prefer the wireless access...     

Improved design of dust test chamber for uniform distribution of dust sedimentation rate

Soiling problems are always encountered for equipment installed in outdoor environments, such as headlamps of automobiles, air conditioners, solar collectors, and so on. How to prevent soiling problems on this equipment is one of the challenges for the design of their external layouts. Thus, evaluations of the dust sedimentation quantities on the surfaces of such equipment are necessary. Outdoor testing is usually straightforward but it takes a long time to experience various environmental parameters, such as dust-laden air, wind speed, wind direction, and so on. Indoor tests, performed in a dust test chamber, are instruments for controlling various environmental parameters independently. The conventional design for a dust test chamber is aimed at providing for a test under extreme environmental conditions. The uniformity of dust sedimentation rate within the chamber is not rigorously controlled. Nevertheless, some applications such as the effect of dust sedimentation on the glazing of solar collector require uniform distribution of dustfall in the test chamber for the indoor (laboratory) test. An improved design for a conventional dust test chamber is proposed. Performance tests done with the remodeled dust test chamber based on the improved design show that the normalized standard deviation of the dustfall concentration can be controlled within 2.41% ± 1.29%.     

Microwave absorbing properties of a radar absorbing structure composed of carbon nanotube papers/glass fabric composites

In this study, carbon nanotube papers were employed in fabricating thin and broadband radar absorbing structures (RAS). Different concentrations of the CNT papers have been made by using a vacuum filtration method, with 20 × 20 cm in size and 21-27 μm in thickness. An epoxy resin was added into the CNT paper and then cured to become a composite with 1-5 wt.% of CNTs and 83-309 μm in thickness. The complex permittivity and permeability (ε′, ε″, μ′, μ″) of the CNT paper composites were measured using the transmission/reflection method in the frequency range of 2-18 GHz. The results reveal that the real (ε′) and imaginary (ε″) parts of the complex permittivity are increased with the CNT concentration. The ε′ of 5 wt.% CNT sample reaches 323 at 2 GHz and then decreases to 49.0 at 18 GHz. The ε″ reaches 321 at 2 GHz and decreases to 26.0 at 18 GHz. The CNT paper composite combined with a glass fabric composite used for a dielectric spacer is fabricated for an innovative RAS and the reflection loss is measured using the arch method in a microwave anechoic chamber. The results show that the 5 wt.% CNT paper composite/glass fabric composite absorbers attain maximum reflection loss of −13.3 dB at 12.0 GHz, −13.8 dB  at 10.0 GHz, and −16.0 dB at 7.5 GHz for spacer thickness of 1.5, 2.0, and 3.0 mm, respectively.